Genetics and Brain Chemistry
Featured Speaker: Dr. J . Dunn BS, DC, CKP, CWK
Mental health imbalances including depression, anxiety, ADD, addictions, and PTSD are rampant in our society. Perhaps some of us are guilty of thinking depressed people in our lives should just “buck up” and be grateful for what they have. Many of these people consider that these conditions are somehow their fault. In working with these patients through the years, I previously had some success—but nothing spectacular - until I began working with the genetic variants. This lead to a greater understanding of the causes of these conditions and greater levels of compassion.
While there can be a myriad of different causes for depression, genetic variants can be particularly causative. Specifically, the vitamin D receptor (VDR) gene can cause a person to be apathetic and depressed due to low dopamine and adrenaline levels. Dopamine is a catecholamine that is a precursor of adrenaline (an adrenal hormone associated with energy). Dopamine has a powerful effect on our reward system. Low dopamine levels have been associated with depression and addictive behavior. In addition, this same genetic variant is responsible for the production of serotonin, our other brain chemical associated with increased mood.